Renal insufficiency in renal insufficiency is caused by many reasons, glomerular serious damage, make the diabetic nephropathy body of clinical syndrome disorder appeared in the excretion of metabolic waste and regulation of water electrolyte and acid-base balance, after the group. Divided into acute renal insufficiency and chronic renal insufficiency. The prognosis of severe, is one of the main diseases threatening the life of the. Renal dysfunction can be divided into the following four stages: in the first stage, renal functional reserve in compensatory stage. Because the kidney reserve compensatory ability greatly, therefore clinical renal function is diminished, but the excretion of metabolites and adjust the balance capacity of water, electrolyte can meet the normal needs, does not appear clinical symptoms, renal function tests are within the normal range or occasionally slightly high phenomenon. The two stage, stage of renal insufficiency. There are many 60%-75%, glomerular damage, renal excretion of metabolic waste when there are some barriers, creatinine and urea nitrogen, can be normal values or beyond. Patients may present with anemia, fatigue, weight loss, is not easy to concentrate spirit etc.. But often overlooked, if there is water loss, infection, hemorrhage and other circumstances, it soon appeared obvious symptoms. The three stage, renal failure stage. Kidney function has been damage is very serious, 75%-95%, stable environment can not maintain the body's internal, were easy to fatigue, weakness, can't concentrate and other symptoms increased significantly, anemia, nocturia, serum creatinine, urea nitrogen increased significantly, and often acid poisoning. This period is also called azotemia. Four stage, period or kidney function not entire end-stage. This period of glomerular damage has been more than 95%, with serious clinical symptoms, such as severe nausea, vomiting, oliguria, IGA Kidney Disease edema, malignant hypertension, severe anemia, skin itching, mouth has the smell of stale urine etc..
Clinical stage is reversible renal fibrosis stage of renal insufficiency in general, as long as to prevent renal function continued to deteriorate, timely repair of renal function, clinical cure and make patients achieve benign disease-free survival is completely possible. At this time to focus on renal insufficiency treatment is blocked from the source, to correct the vasospasm, ensure the smooth blood circulation; in addition the inflammatory medium, induced renal toxicity of various pathogenic factors are inactivated, promote natural cell phenotype conversion to healthy tissue in the reverse.